Yos9, a control protein for misfolded glycosylated and non-glycosylated proteins in ERAD
نویسندگان
چکیده
منابع مشابه
Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins.
Calreticulin (CRT) is thought to be a molecular chaperone that interacts with glycoproteins exclusively through a lectin site specific for monoglucosylated oligosaccharides. However, this chaperone function has never been directly demonstrated nor is it clear how lectin-oligosaccharide interactions facilitate glycoprotein folding. Using purified components, we show that CRT suppresses the aggre...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 2011
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2011.08.021